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human papillary thyroid cancer cell line tpc-1  (DSMZ)


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    DSMZ human papillary thyroid cancer cell line tpc-1
    Human Papillary Thyroid Cancer Cell Line Tpc 1, supplied by DSMZ, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+papillary+thyroid+cancer+cell+line+tpc-1/human+atc+cell+line+8305c/pm35741758-69-9-27
    Average 90 stars, based on 1 article reviews
    human papillary thyroid cancer cell line tpc-1 - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: Identification and Validation of a Prognostic Signature for Thyroid Cancer Based on Ferroptosis-Related Genes.
    Article Snippet: The human anaplastic thyroid cancer cell line 8505c and human papillary thyroid cancer cell line TPC-1 were purchased from the German Collection of Microorganisms and Cell Cultures (DSMZ, Braunschweig, Germany).



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    The conditioned medium of ADSCs enhanced the invasion and migration <t>of</t> <t>TPC-1</t> and <t>BCPAP</t> cells. (A) The supernatant of ADSCs medium was collected and filtered as the conditioned medium. (B) In the transwell assay, the conditioned medium of ADSCs (ADSC-CM) significantly enhanced the invasion of TPC-1/BCPAP cells. (C) In the wound healing assay, ADSC-CM improved the mobility of TPC-1/BCPAP cells. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01, *** p < 0.001.
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    The conditioned medium of ADSCs enhanced the invasion and migration of TPC-1 and BCPAP cells. (A) The supernatant of ADSCs medium was collected and filtered as the conditioned medium. (B) In the transwell assay, the conditioned medium of ADSCs (ADSC-CM) significantly enhanced the invasion of TPC-1/BCPAP cells. (C) In the wound healing assay, ADSC-CM improved the mobility of TPC-1/BCPAP cells. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01, *** p < 0.001.

    Journal: Annals of Medicine

    Article Title: Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway

    doi: 10.1080/07853890.2024.2419990

    Figure Lengend Snippet: The conditioned medium of ADSCs enhanced the invasion and migration of TPC-1 and BCPAP cells. (A) The supernatant of ADSCs medium was collected and filtered as the conditioned medium. (B) In the transwell assay, the conditioned medium of ADSCs (ADSC-CM) significantly enhanced the invasion of TPC-1/BCPAP cells. (C) In the wound healing assay, ADSC-CM improved the mobility of TPC-1/BCPAP cells. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01, *** p < 0.001.

    Article Snippet: The TPC-1 and BCPAP human papillary thyroid cancer cell lines (Procell Life Science & Technology, Co., Ltd.) were cultured in RPMI-1640 medium (Thermo Fisher Scientific, Inc.) containing 10% fetal bovine serum [ , ].

    Techniques: Migration, Transwell Assay, Wound Healing Assay, Standard Deviation

    ADSC-CM Improved the proliferation and viability of TPC-1 and BCPAP cells. (A,C) EdU incorporation assay showed that ADSC-CM upregulated the proliferation of TPC-1 and BCPAP. (B,D) CCK8 assay showed that ADSC-CM increased the cell viability of TPC-1 and BCPAP. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01.

    Journal: Annals of Medicine

    Article Title: Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway

    doi: 10.1080/07853890.2024.2419990

    Figure Lengend Snippet: ADSC-CM Improved the proliferation and viability of TPC-1 and BCPAP cells. (A,C) EdU incorporation assay showed that ADSC-CM upregulated the proliferation of TPC-1 and BCPAP. (B,D) CCK8 assay showed that ADSC-CM increased the cell viability of TPC-1 and BCPAP. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01.

    Article Snippet: The TPC-1 and BCPAP human papillary thyroid cancer cell lines (Procell Life Science & Technology, Co., Ltd.) were cultured in RPMI-1640 medium (Thermo Fisher Scientific, Inc.) containing 10% fetal bovine serum [ , ].

    Techniques: CCK-8 Assay, Standard Deviation

    The conditioned medium of ADSCs upregulated the level of leptin receptor (Ob-R) in TPC-1 and BCPAP cells. (A) The concentration of leptin in the medium of ADSCs was ∼3-fold higher than that in the medium of TPC-1 and BCPAP cells, approximately 50 pg/ml. (B) In vitro experiments showed that ADSC-CM increased the level of leptin receptor (Ob-R) in the TPC-1/BCPAP cells. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, *** p < 0.001.

    Journal: Annals of Medicine

    Article Title: Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway

    doi: 10.1080/07853890.2024.2419990

    Figure Lengend Snippet: The conditioned medium of ADSCs upregulated the level of leptin receptor (Ob-R) in TPC-1 and BCPAP cells. (A) The concentration of leptin in the medium of ADSCs was ∼3-fold higher than that in the medium of TPC-1 and BCPAP cells, approximately 50 pg/ml. (B) In vitro experiments showed that ADSC-CM increased the level of leptin receptor (Ob-R) in the TPC-1/BCPAP cells. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, *** p < 0.001.

    Article Snippet: The TPC-1 and BCPAP human papillary thyroid cancer cell lines (Procell Life Science & Technology, Co., Ltd.) were cultured in RPMI-1640 medium (Thermo Fisher Scientific, Inc.) containing 10% fetal bovine serum [ , ].

    Techniques: Concentration Assay, In Vitro, Standard Deviation

    The neutralizing antibody to leptin reduced the invasion and migration of the TPC-1 and BCPAP cells. ADSC-CM upregulated MMP-2 in TPC-1 and BCPAP cells, and the effect was attenuated by the neutralizing antibody to leptin. (A) Addition of 10 μg/mL NAB of leptin to ADSC-CM conditioned medium attenuated TPC-1 and BCPAP invasion. (B) Leptin NAB also attenuated conditioned medium-promoted TPC-1/BCPAP migration. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, *** p < 0.001.

    Journal: Annals of Medicine

    Article Title: Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway

    doi: 10.1080/07853890.2024.2419990

    Figure Lengend Snippet: The neutralizing antibody to leptin reduced the invasion and migration of the TPC-1 and BCPAP cells. ADSC-CM upregulated MMP-2 in TPC-1 and BCPAP cells, and the effect was attenuated by the neutralizing antibody to leptin. (A) Addition of 10 μg/mL NAB of leptin to ADSC-CM conditioned medium attenuated TPC-1 and BCPAP invasion. (B) Leptin NAB also attenuated conditioned medium-promoted TPC-1/BCPAP migration. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, *** p < 0.001.

    Article Snippet: The TPC-1 and BCPAP human papillary thyroid cancer cell lines (Procell Life Science & Technology, Co., Ltd.) were cultured in RPMI-1640 medium (Thermo Fisher Scientific, Inc.) containing 10% fetal bovine serum [ , ].

    Techniques: Migration, Standard Deviation

    Neutralizing antibodies against leptin slightly downregulated cell proliferation without significant effect on cell viability. (A) Addition of leptin NAB to ADSC-CM slightly reduced the stimulatory effect of conditioned medium on TPC-1 proliferation. (B) Addition of NAB to the conditioned medium had no significant effect on cell viability of TPC-1 cells. (C) NAB of leptin had no significant effect on BCPAP proliferation. (D) NAB of leptin had no significant effect on BCPAP viability. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ns: not statistically significant.

    Journal: Annals of Medicine

    Article Title: Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway

    doi: 10.1080/07853890.2024.2419990

    Figure Lengend Snippet: Neutralizing antibodies against leptin slightly downregulated cell proliferation without significant effect on cell viability. (A) Addition of leptin NAB to ADSC-CM slightly reduced the stimulatory effect of conditioned medium on TPC-1 proliferation. (B) Addition of NAB to the conditioned medium had no significant effect on cell viability of TPC-1 cells. (C) NAB of leptin had no significant effect on BCPAP proliferation. (D) NAB of leptin had no significant effect on BCPAP viability. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ns: not statistically significant.

    Article Snippet: The TPC-1 and BCPAP human papillary thyroid cancer cell lines (Procell Life Science & Technology, Co., Ltd.) were cultured in RPMI-1640 medium (Thermo Fisher Scientific, Inc.) containing 10% fetal bovine serum [ , ].

    Techniques: Standard Deviation

    (A,B) The ADSCs conditioned medium upregulated the MMP-2 levels of TPC-1/BCPAP. NAB of leptin partially counteracted the increase in MMP-2 levels. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01.

    Journal: Annals of Medicine

    Article Title: Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway

    doi: 10.1080/07853890.2024.2419990

    Figure Lengend Snippet: (A,B) The ADSCs conditioned medium upregulated the MMP-2 levels of TPC-1/BCPAP. NAB of leptin partially counteracted the increase in MMP-2 levels. Experiments were repeated at least five times. Data are expressed as mean ± standard deviation. * p < 0.05, ** p < 0.01.

    Article Snippet: The TPC-1 and BCPAP human papillary thyroid cancer cell lines (Procell Life Science & Technology, Co., Ltd.) were cultured in RPMI-1640 medium (Thermo Fisher Scientific, Inc.) containing 10% fetal bovine serum [ , ].

    Techniques: Standard Deviation